Panoply™ Human CYP3A5 Knockdown Stable Cell Line

Name: Panoply™ Human CYP3A5 Knockdown Stable Cell Line
SKU: CSC-DC003971
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC003971

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC003971
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	CYP3A5
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 [ Homo sapiens ]
Gene Symbol	CYP3A5
Synonyms	CYP3A5; cytochrome P450, family 3, subfamily A, polypeptide 5; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5; cytochrome P450 3A5; CP35; P450PCN3; PCN3; cytochrome P-450; niphedipine oxidase; cytochrome P450 HLp2; cytochrome P450-PCN3; microsomal monooxygenase; xenobiotic monooxygenase; aryl hydrocarbon hydroxylase; flavoprotein-linked monooxygenase; CYPIIIA5; FLJ31317; DKFZp686L16231;
Gene ID	1577
Uni Prot ID	P20815
m RNA Refseq	BC033862
Chromosome Location	7q21.1
Function	aromatase activity; electron carrier activ
Pathway	Biological oxidations, organism-specific biosystem; Cytochrome P450 - arranged by substrate type, organism-specific biosystem; Drug metabolism - cytochrome P450, organism-specific biosystem; Drug metabolism - cytochrome P450, conserved biosystem; Drug metabolism - other enzymes, organism-specific biosystem; Drug metabolism - other enzymes, conserved biosystem; Irinotecan Pathway, organism-specific biosystem;
MIM	605325

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