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Panoply™ Human CYP2E1 Knockdown Stable Cell Line

Cat.No.
CSC-DC003961
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
CYP2E1
Synonyms
CPE1; CYP2E; P450-J; P450C2E
Gene Description
cytochrome P450, family 2, subfamily E, polypeptide 1
Gene ID
UniProt ID
P05181
mRNA Refseq
Protein Refseq
Chromosome Location
10q24.3-qter
Function
electron carrier activity; enzyme binding; heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; oxygen binding;
Pathway
Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Biological oxidations, organism-specific biosystem; CYP2E1 reactions, organism-specific biosystem; Chemical carcinogenesis, organism-specific biosystem; Chemical carcinogenesis, conserved biosystem; Cytochrome P450 - arranged by substrate type, organism-specific biosystem;
MIM

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