Panoply™ Human CYLD Knockdown Stable Cell Line

Name: Panoply™ Human CYLD Knockdown Stable Cell Line
SKU: CSC-DC003934
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC003934

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC003934
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	CYLD
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	CYLD cylindromatosis (turban tumor syndrome) [ Homo sapiens ]
Gene Symbol	CYLD
Synonyms	EAC; MFT; SBS; TEM; BRSS; CDMT; MFT1; CYLD1; CYLDI; USPL2
Gene Description	cylindromatosis (turban tumor syndrome)
Gene ID	1540
Uni Prot ID	Q9NQC7
m RNA Refseq	NM_001042355.1
Protein Refseq	NP_001035814.1
Chromosome Location	16q12.1
Function	proline-rich region binding; protein binding; protein kinase binding; ubiquitin thiolesterase activity; ubiquitin-specific protease activity; zinc ion binding;
Pathway	Canonical NF-kappaB pathway, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; NOD1/2 Signaling Pathway, organism-specific biosystem; Negative regulators of RIG-I/MDA5 signaling, organism-specific biosystem; Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, organism-specific biosystem; Osteoclast differentiation, organism-specific biosystem;
MIM	605018

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