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Panoply™ Human CYLD Knockdown Stable Cell Line

Cat.No.
CSC-DC003934
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
CYLD
Synonyms
EAC; MFT; SBS; TEM; BRSS; CDMT; MFT1; CYLD1; CYLDI; USPL2
Gene Description
cylindromatosis (turban tumor syndrome)
Gene ID
UniProt ID
Q9NQC7
mRNA Refseq
Protein Refseq
Chromosome Location
16q12.1
Function
proline-rich region binding; protein binding; protein kinase binding; ubiquitin thiolesterase activity; ubiquitin-specific protease activity; zinc ion binding;
Pathway
Canonical NF-kappaB pathway, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; NOD1/2 Signaling Pathway, organism-specific biosystem; Negative regulators of RIG-I/MDA5 signaling, organism-specific biosystem; Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, organism-specific biosystem; Osteoclast differentiation, organism-specific biosystem;
MIM

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