Panoply™ Human BRIP1 Knockdown Stable Cell Line

Name: Panoply™ Human BRIP1 Knockdown Stable Cell Line
SKU: CSC-DC001538
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC001538

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC001538
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	BRIP1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	BRIP1 BRCA1 interacting protein C-terminal helicase 1 [ Homo sapiens ]
Gene Symbol	BRIP1
Synonyms	BRIP1; BRCA1 interacting protein C-terminal helicase 1; Fanconi anemia group J protein; BACH1; BRCA1/BRCA2 associated helicase 1; FANCJ; OF; ATP-dependent RNA helicase BRIP1; BRCA1/BRCA2-associated helicase 1; BRCA1-associated C-terminal helicase 1; BRCA1-binding helicase-like protein BACH1; FLJ90232; MGC126521; MGC126523;
Gene ID	83990
Uni Prot ID	Q9BX63
m RNA Refseq	BC101472
Chromosome Location	17q22.2
Function	ATP binding; ATP-dependent DNA helicase activity; DNA binding; helicase activity; hydrolase activity, acting on
Pathway	DNA Repair, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem; Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem; Homologous DNA pairing and strand exchange, organism-specific biosystem; Homologous Recombination Repair, organism-specific biosystem; Homologous recombination repair of replication-independent double-strand breaks, organism-specific biosystem;
MIM	605882

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