Panoply™ Human BHLHE41 Knockdown Stable Cell Line

Name: Panoply™ Human BHLHE41 Knockdown Stable Cell Line
SKU: CSC-DC001433
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC001433

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC001433
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	BHLHE41
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	BHLHE41 basic helix-loop-helix family, member e41 [ Homo sapiens ]
Gene Symbol	BHLHE41
Synonyms	DEC2; hDEC2; BHLHB3; SHARP1
GeneID	79365
Uni ProtID	Q8TAT1
mRNA Refseq	NM_030762.2
Protein Refseq	NP_110389.1
Chromosome Location	12p12.1
Function	E-box binding; E-box binding; MRF binding; RNA polymerase II activating transcription factor binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; bHLH transcription factor binding; bHLH transcription factor binding; histone deacetylase binding; protein heterodimerization activity; protein heterodimerization activity; protein homodimerization activity; sequence-specific DNA binding transcription factor activity;
Pathway	BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; Circadian Clock, organism-specific biosystem; Circadian rhythm - mammal, organism-specific biosystem; Circadian rhythm - mammal, conserved biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem;
MIM	606200

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