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Panoply™ Human BAK1 Knockdown Stable Cell Line

Cat.No.
CSC-DC001316
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
BAK1
Synonyms
BAK; CDN1; BCL2L7; BAK-LIKE
Gene Description
BCL2-antagonist/killer 1
Gene ID
UniProt ID
Q16611
mRNA Refseq
Protein Refseq
Chromosome Location
6p21.3
Function
BH domain binding; chaperone binding; heat shock protein binding; identical protein binding; metal ion binding; protein binding; protein heterodimerization activity; protein homodimerization activity;
Pathway
Activation and oligomerization of BAK protein, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis Modulation and Signaling, organism-specific biosystem; DNA damage response (only ATM dependent), organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; Integrated Breast Cancer Pathway, organism-specific biosystem;
MIM

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