Panoply™ Human ATP6V1E2 Knockdown Stable Cell Line

Name: Panoply™ Human ATP6V1E2 Knockdown Stable Cell Line
SKU: CSC-DC001190
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC001190

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC001190
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ATP6V1E2
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2 [ Homo sapiens ]
Gene Symbol	ATP6V1E2
Synonyms	VMA4; ATP6E1; ATP6EL2; ATP6V1EL2
Gene Description	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
Gene ID	90423
Uni Prot ID	Q96A05
m RNA Refseq	NM_080653.3
Protein Refseq	NP_542384.1
Chromosome Location	2p21
Function	hydrogen-exporting ATPase activity, phosphorylative mechanism; proton-transporting ATPase activity, rotational mechanism;
Pathway	Collecting duct acid secretion, organism-specific biosystem; Collecting duct acid secretion, conserved biosystem; Disease, organism-specific biosystem; Epithelial cell signaling in Helicobacter pylori infection, organism-specific biosystem; Epithelial cell signaling in Helicobacter pylori infection, conserved biosystem; Insulin receptor recycling, organism-specific biosystem; Iron uptake and transport, organism-specific biosystem;

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