Panoply™ Human ATP2B3 Knockdown Stable Cell Line

Name: Panoply™ Human ATP2B3 Knockdown Stable Cell Line
SKU: CSC-DC001146
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC001146

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC001146
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ATP2B3
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 [ Homo sapiens ]
Gene Symbol	ATP2B3
Synonyms	ATP2B3; ATPase, Ca++ transporting, plasma membrane 3; plasma membrane calcium-transporting ATPase 3; plasma membrane calcium transporting ATPase 3; PMCA3; plasma membrane calcium pump; plasma membrane calcium ATPase; PMCA3a;
Gene ID	492
Uni Prot ID	Q16720
m RNA Refseq	BC130009
Chromosome Location	Xq28
Function	ATP binding; calcium-transporting ATPase activity; calmodulin binding; hydrolase activity; hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances; metal ion binding; nucleotide binding;
Pathway	Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Hemostasis, organism-specific biosystem; Ion channel transport, organism-specific biosystem; Ion transport by P-type ATPases, organism-specific biosystem; Pancreatic secretion, organism-specific biosystem;
MIM	300014

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