Panoply™ Human ARHGEF7 Knockdown Stable Cell Line

Name: Panoply™ Human ARHGEF7 Knockdown Stable Cell Line
SKU: CSC-DC000902
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC000902

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC000902
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ARHGEF7
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 [ Homo sapiens ]
Gene Symbol	ARHGEF7
Synonyms	P50; P85; PAK3; PIXB; COOL1; P50BP; COOL-1; P85SPR; BETA-PIX; P85COOL1; Nbla10314
Gene Description	Rho guanine nucleotide exchange factor (GEF) 7
Gene ID	8874
Uni Prot ID	Q14155
m RNA Refseq	NM_003899.3
Protein Refseq	NP_003890.1
Chromosome Location	13q34
Pathway	Aurora A signaling, organism-specific biosystem; CDC42 signaling events, organism-specific biosystem; Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; Class I PI3K signaling events, organism-specific biosystem; Disease, organism-specific biosystem; EGFR downregulation, organism-specific biosystem; G alpha (12/13) signalling events, organism-specific biosystem;
MIM	605477

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