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Panoply™ Human ARHGEF16 Knockdown Stable Cell Line

Cat.No.
CSC-DC000884
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
ARHGEF16
Synonyms
ARHGEF16; Rho guanine nucleotide exchange factor (GEF) 16; rho guanine nucleotide exchange factor 16; GEF16; NBR; putative neuroblastoma protein; ephexin-4; Rho guanine exchange factor (GEF) 16;
Gene ID
UniProt ID
Q5VV41
mRNA Refseq
BC002681
Chromosome Location
1p36.3
Function
PDZ domain binding; Rho GTPase binding; Rho guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; protein binding; receptor tyrosine kinase binding;
Pathway
Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; G alpha (12/13) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; NRAGE signals death through JNK, organism-specific biosystem; Rho GTPase cycle, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by GPCR, organism-specific biosystem;

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