Panoply™ Human ARHGEF12 Knockdown Stable Cell Line

Name: Panoply™ Human ARHGEF12 Knockdown Stable Cell Line
SKU: CSC-DC000882
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC000882

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC000882
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ARHGEF12
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 [ Homo sapiens ]
Gene Symbol	ARHGEF12
Synonyms	LARG; PRO2792
GeneID	23365
Uni ProtID	B4E2K6
mRNA Refseq	NM_001198665.1
Protein Refseq	NP_001185594.1
Chromosome Location	11q23.3
Function	G-protein coupled receptor binding; GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; phospholipid binding; protein binding;
Pathway	Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; Developmental Biology, organism-specific biosystem; G alpha (12/13) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem;
MIM	604763

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