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Panoply™ Human ARHGEF11 Knockdown Stable Cell Line

Cat.No.
CSC-DC000881
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
ARHGEF11
Synonyms
GTRAP48; PDZ-RHOGEF
Gene ID
UniProt ID
O15085
mRNA Refseq
Protein Refseq
Chromosome Location
1q21
Function
G-protein coupled receptor binding; GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; phospholipid binding; protein binding;
Pathway
Axon guidance, organism-specific biosystem; Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; Developmental Biology, organism-specific biosystem; G alpha (12/13) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; NRAGE signals death through JNK, organism-specific biosystem; Regulation of RhoA activity, organism-specific biosystem;
MIM

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