Panoply™ Human ARAP3 Knockdown Stable Cell Line

Name: Panoply™ Human ARAP3 Knockdown Stable Cell Line
SKU: CSC-DC000825
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC000825

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC000825
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ARAP3
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 [ Homo sapiens ]
Gene Symbol	CENTD3
Synonyms	DRAG1; CENTD3
Gene Description	centaurin, delta 3
GeneID	64411
Uni ProtID	Q05CH1
mRNA Refseq	NM_022481.5
Protein Refseq	NP_071926.4
Chromosome Location	5q31.3
Function	ARF GTPase activator activity; NOT Rac GTPase activator activity; Rho GTPase activator activity; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; zinc ion binding;
Pathway	Class I PI3K signaling events, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Regulation of RhoA activity, organism-specific biosystem; Rho GTPase cycle, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by Rho GTPases, organism-specific biosystem;
MIM	606647

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