Panoply™ Human APOA5 Knockdown Stable Cell Line

Name: Panoply™ Human APOA5 Knockdown Stable Cell Line
SKU: CSC-DC000769
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC000769

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC000769
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	APOA5
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	APOA5 apolipoprotein A-V [ Homo sapiens ]
Gene Symbol	APOA5
Synonyms	RAP3; APOAV
Gene ID	116519
Uni Prot ID	Q6Q788
m RNA Refseq	NM_001166598.1
Protein Refseq	NP_001160070.1
Chromosome Location	11q23
Function	enzyme activator activity; enzyme binding; heparin binding; contributes_to heparin binding; lipase activator activity; lipid binding; lipoprotein lipase activator activity; lipoprotein particle receptor binding; low-density lipoprotein particle receptor binding; phosphatidylcholine binding; phospholipid binding; protein binding;
Pathway	Chylomicron-mediated lipid transport, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Lipid digestion, mobilization, and transport, organism-specific biosystem; Lipoprotein metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPAR signaling pathway, organism-specific biosystem;
MIM	606368

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