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Panoply™ Human APH1B Knockdown Stable Cell Line

Cat.No.
CSC-DC000754
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
APH1B
Synonyms
APH1B; anterior pharynx defective 1 homolog B (C. elegans); gamma-secretase subunit APH-1B; APH 1B; DKFZp564D0372; PSFL; aph-1beta; APH-1B; PRO1328; TAAV688; FLJ33115;
Gene ID
UniProt ID
Q8WW43
mRNA Refseq
BC020905
Chromosome Location
15q22.2
Function
aspartic-type endopeptidase activity; endopeptidase activity; peptidase activity; peptidase activity; protein binding;
Pathway
Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; NRIF signals cell death from the nucleus, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Nuclear signaling by ERBB4, organism-specific biosystem; Presenilin action in Notch and Wnt signaling, organism-specific biosystem;
MIM

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