Panoply™ Human ADCY8 Knockdown Stable Cell Line

Name: Panoply™ Human ADCY8 Knockdown Stable Cell Line
SKU: CSC-DC000290
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC000290

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC000290
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ADCY8
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ADCY8 adenylate cyclase 8 (brain) [ Homo sapiens ]
Gene Symbol	ADCY8
Synonyms	AC8; ADCY3; HBAC1
Gene Description	adenylate cyclase 8 (brain)
Gene ID	114
Uni Prot ID	P40145
m RNA Refseq	NM_001115.2
Protein Refseq	NP_001106.1
Chromosome Location	8q24
Function	ATP binding; adenylate cyclase activity; calcium- and calmodulin-responsive adenylate cyclase activity; metal ion binding;
Pathway	Activation of GABAB receptors, organism-specific biosystem; Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Adenylate cyclase activating pathway, organism-specific biosystem; Adenylate cyclase inhibitory pathway, organism-specific biosystem; Aquaporin-mediated transport, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem;
MIM	103070

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