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Panoply™ Human ADAM10 Knockdown Stable Cell Line

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Cat.No.
CSC-DC000228
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
ADAM10
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Official Symbol
ADAM10
Synonyms
kuz; AD10; MADM; CD156c; HsT18717
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
O14672
Chromosome Location
15q22
Pathway
Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Alzheimers Disease, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; Disease, organism-specific biosystem; Epithelial cell signaling in Helicobacter pylori infection, organism-specific biosystem;
Function
SH3 domain binding; endopeptidase activity; integrin binding; metalloendopeptidase activity; metalloendopeptidase activity; metallopeptidase activity; metallopeptidase activity; metallopeptidase activity; protein binding; protein homodimerization activity; protein kinase binding; receptor binding; zinc ion binding;

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