Panoply™ Human ACVR1C Knockdown Stable Cell Line

Name: Panoply™ Human ACVR1C Knockdown Stable Cell Line
SKU: CSC-DC000216
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC000216

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-DC000216
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ACVR1C
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ACVR1C activin A receptor, type IC [ Homo sapiens ]
Gene Symbol	ACVR1C
Synonyms	ALK7; ACVRLK7
Gene Description	activin A receptor, type IC
Gene ID	130399
Uni Prot ID	Q8NER5
m RNA Refseq	NM_145259.2
Protein Refseq	NP_660302.2
Chromosome Location	2q24.1
Function	ATP binding; activin receptor activity, type I; metal ion binding; nodal binding; transforming growth factor beta-activated receptor activity;
Pathway	Developmental Biology, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; Regulation of Signaling by NODAL, organism-specific biosystem; Signaling by NODAL, organism-specific biosystem; TGF-beta signaling pathway, organism-specific biosystem; TGF-beta signaling pathway, conserved biosystem;
MIM	608981

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