Panoply™ Human ACACB Knockdown Stable Cell Line

Name: Panoply™ Human ACACB Knockdown Stable Cell Line
SKU: CSC-DC000110
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC000110

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC000110
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ACACB
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ACACB acetyl-CoA carboxylase beta [ Homo sapiens ]
Gene Symbol	ACACB
Synonyms	ACC2; ACCB; HACC275
Gene Description	acetyl-Coenzyme A carboxylase beta
Gene ID	32
Uni Prot ID	O00763
m RNA Refseq	NM_001093.3
Protein Refseq	NP_001084.3
Chromosome Location	12q24.11
Function	ATP binding; acetyl-CoA carboxylase activity; biotin carboxylase activity; metal ion binding; protein binding;
Pathway	AMPK signaling, organism-specific biosystem; Activation of Gene Expression by SREBP (SREBF), organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; ChREBP activates metabolic gene expression, organism-specific biosystem; Fatty Acid Biosynthesis, organism-specific biosystem; Fatty acid biosynthesis, organism-specific biosystem;
MIM	601557

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