Panoply™ Human ABI1 Knockdown Stable Cell Line

Name: Panoply™ Human ABI1 Knockdown Stable Cell Line
SKU: CSC-DC000090
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC000090

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC000090
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ABI1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ABI1 abl-interactor 1 [ Homo sapiens ]
Gene Symbol	ABI1
Synonyms	E3B1; ABI-1; ABLBP4; NAP1BP; SSH3BP; SSH3BP1
Gene ID	10006
Uni Prot ID	Q8IZP0
m RNA Refseq	NM_001012750.2
Protein Refseq	NP_001012768.1
Chromosome Location	10p11.2
Function	cytoskeletal protein binding; protein binding; protein tyrosine kinase activator activity;
Pathway	E-cadherin signaling in the nascent adherens junction, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; ErbB1 downstream signaling, organism-specific biosystem; RAC1 signaling pathway, organism-specific biosystem; Regulation of RAC1 activity, organism-specific biosystem; Stabilization and expansion of the E-cadherin adherens junction, organism-specific biosystem;
MIM	603050

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