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Human hRad54 Knockdown Cell Line-HeLa

Cat.No.
CSC-RK0021
Abbr
HeLa-HuhRad54 Knockdown
Alias
RAD54L,hHR54,hRAD54,RAD54A,HR54,
Growth Properties
Adherent
Host Cell
HeLa
Morphology
Epithelial
Shipping
Dry ice
Species
Human
Background
The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.

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