Human hRad54 Knockdown Cell Line-HeLa

Name: Human hRad54 Knockdown Cell Line-HeLa
SKU: CSC-RK0021
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RK0021

Host Cell : HeLa Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-RK0021
Background	The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.
Target Gene	RAD54L
Abbr	HeLa-HuhRad54 Knockdown
Alias	RAD54L, hHR54, hRAD54, RAD54A, HR54
Host Cell	HeLa
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Morphology	Epithelial
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	RAD54L RAD54-like (S. cerevisiae) [ Homo sapiens ]
Gene Symbol	RAD54L
Synonyms	RAD54L; RAD54-like (S. cerevisiae); RAD54 (S.cerevisiae) like; DNA repair and recombination protein RAD54-like; hHR54; hRAD54; RAD54A; RAD54 homolog; HR54;
GeneID	8438
Uni ProtID	Q92698
mRNA Refseq	BC121059
Chromosome Location	1p32
Function	ATP binding; DNA binding; helicase activity; hydrolase activity, acting on acid anhydrides; nucleotide binding;
Pathway	Homologous recombination, organism-specific biosystem; Homologous recombination, conserved biosystem;
MIM	603615

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