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Human hRad54 Knockdown Cell Line-HeLa

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Cat.No.
CSC-RK0021
Background
The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HeLa
Ship
Dry ice
Gene Information
Official Symbol
RAD54L
Synonyms
RAD54L; RAD54-like (S. cerevisiae); RAD54 (S.cerevisiae) like; DNA repair and recombination protein RAD54-like; hHR54; hRAD54; RAD54A; RAD54 homolog; HR54;
Gene ID
MIM
UniProt ID
Q92698
Chromosome Location
1p32
Pathway
Homologous recombination, organism-specific biosystem; Homologous recombination, conserved biosystem;
Function
ATP binding; DNA binding; helicase activity; hydrolase activity, acting on acid anhydrides; nucleotide binding;

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