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Human XRCC3 Knockdown Cell Line-LN428 Glioma

Cat.No.
CSC-RK0249
Abbr
LN428 Glioma-HuXRCC3 Knockdown
Alias
XRCC3,CMM6,
Growth Properties
Adherent
Host Cell
LN428 glioma
Morphology
Epithelial
Shipping
Dry ice
Species
Human
Background
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.

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