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Human WRAP73 Knockdown Cell Line-HeLa

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-RK0299

Host Cell :   HeLa Validation :   Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No. CSC-RK0299
Background This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Studies of the related mouse protein suggest that the encoded protein may play a role in the process of ossification.
Target Gene WRAP73
Abbr HeLa-HuWRAP73 Knockdown
Alias WRAP73, WDR8, FLJ20430, MGC99569
Host Cell HeLa
Host Cell Species Homo sapiens (Human)
Applications

(1) Studying gene functions

(2) Studying gene interactions and signaling pathways

(3) Target validation and drug discovery

(4) Designing diseases models

Morphology Epithelial
Size >1 × 106 cells / vial
Stability Validated for at least 10 passages
Validation Real-Time RCR
Shipping Dry ice
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name WRAP73 WD repeat containing, antisense to TP73 [ Homo sapiens ]
Gene Symbol WRAP73
Synonyms WDR8
Gene ID 49856
Uni Prot ID Q9P2S5
m RNA Refseq BC002611
Chromosome Location 1p36.3
MIM 606040
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