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Human UNG Knockdown Cell Line-LN428 Glioma

See other products for UNG
Cat.No.
CSC-RK0218
Background
This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
LN428 glioma
Ship
Dry ice
Gene Information
Official Symbol
UNG
Synonyms
UNG; uracil-DNA glycosylase; DGU; HIGM4; UDG; UNG1; UNG2; uracil DNA glycosylase 1; uracil DNA glycosylase 2; uracil-DNA glycosylase 1, uracil-DNA glycosylase 2; UNG15; DKFZp781L1143;
Gene ID
MIM
UniProt ID
P13051
Chromosome Location
12q23-q24.1
Pathway
Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Primary immunodeficiency, organism-specific biosystem; Primary immunodeficiency, conserved biosystem;
Function
hydrolase activity, hydrolyzing N-glycosyl compounds; uracil DNA N-glycosylase activity; uracil DNA N-glycosylase activity;
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Cat#
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Titer
Product Size
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AD17385Z
>1x 10^9 vp/ml
1 x 0.2 ml
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