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Human TXNRD2 Knockdown Cell Line-HeLa

Cat.No.
CSC-RK0296
Abbr
HeLa-HuTXNRD2 Knockdown
Alias
TXNRD2,TR,TR3,TRXR2,SELZ,TR-BETA,
Growth Properties
Adherent
Host Cell
HeLa
Morphology
Epithelial
Shipping
Dry ice
Species
Human
Background
Thioredoxin reductase (TR) is a dimeric NADPH-dependent FAD containing enzyme that catalyzes the reduction of the active site disulfide of thioredoxin and other substrates. TR is a member of a family of pyridine nucleotide-disulfide oxidoreductases and is a key enzyme in the regulation of the intracellular redox environment. Three thioredoxin reductase genes have been found that encode selenocysteine containing proteins. This gene partially overlaps the COMT gene on chromosome 22.

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