Human TRIO Knockdown Cell Line-HeLa

Name: Human TRIO Knockdown Cell Line-HeLa
SKU: CSC-RK0038
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RK0038

Host Cell : HeLa Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-RK0038
Background	Promotes the exchange of GDP by GTP. Together with leukocyte antigen-related (LAR) protein, it could play a role in coordinating cell-matrix and cytoskeletal rearrangements necessary for cell migration and cell growth.
Target Gene	TRIO
Abbr	HeLa-HuTRIO Knockdown
Host Cell	HeLa
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Morphology	Epithelial
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TRIO trio Rho guanine nucleotide exchange factor [ Homo sapiens ]
Gene Symbol	TRIO
Synonyms	tgat; ARHGEF23
Gene Description	triple functional domain (PTPRF interacting)
GeneID	7204
Uni ProtID	O75962
mRNA Refseq	NM_007118.2
Protein Refseq	NP_009049.2
Chromosome Location	5p15.2
Function	ATP binding; Rho guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; phospholipid binding; protein binding; protein serine/threonine kinase activity;
Pathway	Axon guidance, organism-specific biosystem; Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; DCC mediated attractive signaling, organism-specific biosystem; Developmental Biology, organism-specific biosystem; G alpha (12/13) signalling events, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem;
MIM	601893

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