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Human TMSB4X Knockdown Cell Line-HeLa

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-RK0293

Host Cell :   HeLa Validation :   Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No. CSC-RK0293
Background This gene encodes an actin sequestering protein which plays a role in regulation of actin polymerization. The protein is also involved in cell proliferation, migration, and differentiation. This gene escapes X inactivation and has a homolog on chromosome Y.
Target Gene TMSB4X
Abbr HeLa-HuTMSB4X Knockdown
Alias TMSB4X, TB4X, FX, PTMB4, TMSB4
Host Cell HeLa
Host Cell Species Homo sapiens (Human)
Applications

(1) Studying gene functions

(2) Studying gene interactions and signaling pathways

(3) Target validation and drug discovery

(4) Designing diseases models

Morphology Epithelial
Size >1 × 106 cells / vial
Stability Validated for at least 10 passages
Validation Real-Time RCR
Shipping Dry ice
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name TMSB4X thymosin beta 4, X-linked [ Homo sapiens ]
Gene Symbol TMSB4X
Synonyms TMSB4X; thymosin beta 4, X-linked; thymosin, beta 4, X chromosome , TMSB4; thymosin beta-4; TB4X; t beta-4; prothymosin beta-4; thymosin, beta 4, X chromosome; FX; PTMB4; TMSB4;
Gene ID 7114
Uni Prot ID P62328
m RNA Refseq BC101790
Chromosome Location Xq21.3-q22
Function actin binding; protein binding;
Pathway Hemostasis, organism-specific biosystem; Platelet activation, signaling and aggregation, organism-specific biosystem; Platelet degranulation, organism-specific biosystem; Regulation of Actin Cytoskeleton, organism-specific biosystem; Regulation of actin cytoskeleton, organism-specific biosystem; Regulation of actin cytoskeleton, conserved biosystem; Response to elevated platelet cytosolic Ca2+, organism-specific biosystem;
MIM 300159
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