Human SRI Knockdown Cell Line-HeLa

Name: Human SRI Knockdown Cell Line-HeLa
SKU: CSC-RK0289
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RK0289

Host Cell : HeLa Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-RK0289
Background	This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene.
Target Gene	SRI
Abbr	HeLa-HuSRI Knockdown
Alias	SRI, sorcin, SCN, V19, CP22, CP-22, FLJ26259
Host Cell	HeLa
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Morphology	Epithelial
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	SRI sorcin [ Homo sapiens ]
Gene Symbol	SRI
Synonyms	SCN; V19; CP22; CP-22
Gene Description	sorcin
GeneID	6717
Uni ProtID	A8MTH6
mRNA Refseq	NM_198901.1
Protein Refseq	NP_944490.1
Chromosome Location	7q21.1
Function	calcium channel regulator activity; calcium ion binding; protein binding; protein heterodimerization activity; receptor binding;
MIM	182520

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