Human SIRT5 Knockdown Cell Line - Glioma

Name: Human SIRT5 Knockdown Cell Line - Glioma
SKU: CSC-RK0238
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RK0238

Host Cell : Glioma Validation : Real-Time RCR

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RK0238
Description	This cell line is engineered to stably express shRNA targeting human SIRT5.
Target Gene	SIRT5
Host Cell	Glioma
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Storage	Liquid nitrogen
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	SIRT5 sirtuin 5 [ Homo sapiens ]
Gene Symbol	SIRT5
Synonyms	SIR2L5
GeneID	23408
Uni ProtID	Q9NXA8
mRNA Refseq	NM_001193267.2
Protein Refseq	NP_001180196.1
Chromosome Location	6p23
Function	NOT NAD+ ADP-ribosyltransferase activity; NAD+ binding; protein-malonyllysine demalonylase activity; protein-succinyllysine desuccinylase activity; zinc ion binding;
Pathway	Signaling events mediated by HDAC Class I, organism-specific biosystem;
MIM	604483

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