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Human RHOQ Knockdown Cell Line-HeLa

Human RHOQ Knockdown Cell Line-HeLa

Cat.No. :  CSC-RK0286

Host Cell:  HeLa Validation:  Real-Time RCR

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Cell Line Information

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Cat. No. CSC-RK0286
Gene RHOQ
Alias RHOQ, TC10, ARHQ, TC10A, RASL7A
Host Cell HeLa
Host Cell Species Homo sapiens (Human)
Morphology Epithelial
Stability Validated for at least 10 passages
Application

(1) Studying gene functions

(2) Studying gene interactions and signaling pathways

(3) Target validation and drug discovery

(4) Designing diseases models

Size Form >1 × 10^6 cells / vial
Shipping Dry ice
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations

The following safety precautions should be observed.

1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.

2. No eating, drinking or smoking while handling the stable line.

3. Wash hands after handling the stable line and before leaving the lab.

4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.

5. All waste should be considered hazardous.

6. Dispose of all liquid waste after each experiment and treat with bleach.

Ship Dry ice
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This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14.
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