Human PRDX2 Knockdown Cell Line-HeLa

Name: Human PRDX2 Knockdown Cell Line-HeLa
SKU: CSC-RK0284
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RK0284

Host Cell : HeLa Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-RK0284
Background	This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. The crystal structure of this protein has been resolved to 2.7 angstroms. Transcript variants encoding distinct isoforms have been identified for this gene.
Target Gene	PRDX2
Abbr	HeLa-HuPRDX2 Knockdown
Alias	PRDX2, TDPX1, MGC4104, NKEFB, PRP, PRX2, PRXII, torin, TSA, NKEF-B, TPX1
Host Cell	HeLa
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Morphology	Epithelial
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	PRDX2 peroxiredoxin 2 [ Homo sapiens ]
Gene Symbol	PRDX2
Synonyms	PRP; TSA; PRX2; PTX1; TPX1; NKEFB; PRXII; TDPX1
Gene Description	peroxiredoxin 2
Gene ID	7001
Uni Prot ID	P32119
m RNA Refseq	NM_181738.1
Protein Refseq	NP_859428.1
Chromosome Location	19p13.2
Function	antioxidant activity; antioxidant activity; thioredoxin peroxidase activity; thioredoxin peroxidase activity;
Pathway	Selenium Pathway, organism-specific biosystem;
MIM	600538

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