Human PIK3CD Knockdown Cell Line-HeLa

Name: Human PIK3CD Knockdown Cell Line-HeLa
SKU: CSC-RK0281
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RK0281

Host Cell : HeLa Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-RK0281
Background	Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.
Target Gene	PIK3CD
Abbr	HeLa-HuPIK3CD Knockdown
Alias	PIK3CD, PI3Kdelta, PI3K, P110DELTA
Host Cell	HeLa
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Morphology	Epithelial
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta [ Homo sapiens ]
Gene Symbol	PIK3CD
Synonyms	PI3K; p110D; P110DELTA
Gene ID	5293
Uni Prot ID	A7E2E0
m RNA Refseq	NM_005026.3
Protein Refseq	NP_005017.3
Chromosome Location	1p36.2
Function	1-phosphatidylinositol-3-kinase activity; ATP binding; phosphatidylinositol 3-kinase activity; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; protein binding;
Pathway	3-phosphoinositide biosynthesis, organism-specific biosystem; 3-phosphoinositide biosynthesis, conserved biosystem; AMPK signaling, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, organism-specific biosystem;
MIM	602839

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