Human PARG Knockdown Cell Line-HeLa

Name: Human PARG Knockdown Cell Line-HeLa
SKU: CSC-RK0044
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RK0044

Host Cell : HeLa Validation : Real-Time RCR

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RK0044
Background	Poly(ADP-ribose) glycohydrolase (PARG) is the major enzyme responsible for the catabolism of poly(ADP-ribose), a reversible covalent-modifier of chromosomal proteins. The protein is found in many tissues and may be subject to proteolysis generating smaller, active products.
Target Gene	PARG
Abbr	HeLa-HuPARG Knockdown
Alias	PARG, PARG99, FLJ54459, FLJ60257, FLJ60456
Host Cell	HeLa
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Morphology	Epithelial
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	PARG poly (ADP-ribose) glycohydrolase [ Homo sapiens ]
Gene Symbol	PARG
Synonyms	PARG99
Gene Description	poly (ADP-ribose) glycohydrolase
GeneID	8505
Uni ProtID	Q86W56
mRNA Refseq	NM_003631.2
Protein Refseq	NP_003622.2
Chromosome Location	10q11.23
Function	chromatin binding; poly(ADP-ribose) glycohydrolase activity;
MIM	603501

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