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Human NFE2L2 Knockdown Cell Line-HeLa

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Cat.No.
CSC-RK0277
Background
This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HeLa
Ship
Dry ice
Gene Information
Official Symbol
NFE2L2
Synonyms
NFE2L2; nuclear factor (erythroid-derived 2)-like 2; nuclear factor erythroid 2-related factor 2; NF E2 related factor 2; NRF2; HEBP1; NFE2-related factor 2; NF-E2-related factor 2; nuclear factor erythroid-derived 2-like 2; nuclear factor, erythroid derived 2, like 2;
Gene ID
MIM
UniProt ID
Q16236
Chromosome Location
2q31
Pathway
Keap1-Nrf2 Pathway, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem;
Function
DNA binding; protein dimerization activity; protein domain specific binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;

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