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Human NF1 Knockdown Cell Line-HeLa

Cat.No.
CSC-RK0276
Abbr
HeLa-HuNF1 Knockdown
Alias
NF1,WSS,NFNS,VRNF,FLJ21220,DKFZp686J1293,
Growth Properties
Adherent
Host Cell
HeLa
Morphology
Epithelial
Shipping
Dry ice
Species
Human
Background
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

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