Human MLH3 Knockdown Cell Line - Glioma

Name: Human MLH3 Knockdown Cell Line - Glioma
SKU: CSC-RK0233
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RK0233

Host Cell : Glioma Validation : Real-Time RCR

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RK0233
Description	This cell line is engineered to stably express shRNA targeting human MLH3.
Target Gene	MLH3
Host Cell	Glioma
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Storage	Liquid nitrogen
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	MLH3 mutL homolog 3 (E. coli) [ Homo sapiens ]
Gene Symbol	MLH3
Synonyms	HNPCC7
Gene Description	mutL homolog 3 (E. coli)
Gene ID	27030
Uni Prot ID	Q9UHC1
m RNA Refseq	NM_001040108.1
Protein Refseq	NP_001035197.1
Chromosome Location	14q24.3
Function	ATP binding; ATPase activity; MutSalpha complex binding; centromeric DNA binding; chromatin binding; mismatched DNA binding; protein binding; satellite DNA binding; single-stranded DNA binding;
Pathway	Meiosis, organism-specific biosystem; Meiotic Recombination, organism-specific biosystem; Mismatch repair, organism-specific biosystem; Mismatch repair, conserved biosystem;
MIM	604395

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