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Human GNAQ Knockdown Cell Line-HeLa

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Cat.No.
CSC-RK0271
Background
This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HeLa
Ship
Dry ice
Gene Information
Official Symbol
GNAQ
Synonyms
GNAQ; guanine nucleotide binding protein (G protein), q polypeptide; guanine nucleotide-binding protein G(q) subunit alpha; G ALPHA q; GAQ; guanine nucleotide-binding protein alpha-q; G-ALPHA-q;
Gene ID
MIM
UniProt ID
P50148
Chromosome Location
9q21
Pathway
ADP signalling through P2Y purinoceptor 1, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem;
Function
G-protein beta/gamma-subunit complex binding; G-protein coupled receptor binding; GTP binding; GTPase activator activity; GTPase activity; guanyl nucleotide binding; guanyl-nucleotide exchange factor activity; metal ion binding; nucleotide binding; phospholipase C activity; protein binding; signal transducer activity;

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