Human EPAS1 Knockdown Cell Line-HeLa

Name: Human EPAS1 Knockdown Cell Line-HeLa
SKU: CSC-RK0274
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RK0274

Host Cell : HeLa Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-RK0274
Background	This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.
Target Gene	EPAS1
Abbr	HeLa-HuEPAS1 Knockdown
Alias	EPAS1, bHLHe73, HIF2A, HLF, MOP2, PASD2, EPAS-1, ECYT4
Host Cell	HeLa
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Morphology	Epithelial
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	Homo sapiens endothelial PAS domain protein 1 DNA.
Gene Symbol	EPAS1
Synonyms	HLF; MOP2; ECYT4; HIF2A; PASD2; bHLHe73;EPAS1
mRNA Refseq	BC015869

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