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Human EIF2C2 Knockdown Cell Line-HeLa

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Cat.No.
CSC-RK0256
Background
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HeLa
Ship
Dry ice
Gene Information
Official Symbol
EIF2C2
Synonyms
EIF2C2; eukaryotic translation initiation factor 2C, 2; protein argonaute-2; AGO2; argonaute 2; Q10; PPD; hAgo2; eIF2C 2; eIF-2C 2; argonaute2; protein slicer; PAZ Piwi domain protein; MGC3183;
Gene ID
MIM
UniProt ID
Q9UKV8
Chromosome Location
8q24
Pathway
Gene Expression, organism-specific biosystem; MicroRNA (miRNA) Biogenesis, organism-specific biosystem; Post-transcriptional Silencing By Small RNAs, organism-specific biosystem; Pre-NOTCH Expression and Processing, organism-specific biosystem; Pre-NOTCH Transcription and Translation, organism-specific biosystem; Regulatory RNA pathways, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
Function
RNA 7-methylguanosine cap binding; endonuclease activity; endoribonuclease activity, cleaving siRNA-paired mRNA; hydrolase activity; metal ion binding; protein binding; siRNA binding; contributes_to siRNA binding; translation initiation factor activity;

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