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Human BID Knockdown Cell Line-HeLa

Cat.No.
CSC-RK0258
Human BID Knockdown Cell Line-HeLa
Abbr
HeLa-HuBID Knockdown
Alias
BID,p22 BID,FP497,MGC15319,MGC42355,
Growth Properties
Adherent
Host Cell
HeLa
Morphology
Epithelial
Shipping
Dry ice
Species
Human
Background
This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

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