Human ATP6AP2 Knockdown Cell Line-HeLa

Name: Human ATP6AP2 Knockdown Cell Line-HeLa
SKU: CSC-RK0031
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RK0031

Host Cell : HeLa Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-RK0031
Background	This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases.
Target Gene	ATP6AP2
Abbr	HeLa-HuATP6AP2 Knockdown
Alias	ATP6AP2, ELDF10, ATP6IP2, MSTP009, APT6M8-9, ATP6M8-9, MGC99577
Host Cell	HeLa
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Morphology	Epithelial
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 [ Homo sapiens ]
Gene Symbol	ATP6AP2
Synonyms	M8-9; MRXE; XMRE; HT028; ELDF10; ATP6IP2; MSTP009; APT6M8-9; ATP6M8-9
Gene Description	ATPase, H+ transporting, lysosomal accessory protein 2
Gene ID	10159
Uni Prot ID	O75787
m RNA Refseq	NM_005765.2
Protein Refseq	NP_005756.2
Chromosome Location	Xp11.4
Function	protein binding; receptor activity;
Pathway	ACE Inhibitor Pathway, organism-specific biosystem; Metabolism of Angiotensinogen to Angiotensins, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Oxidative phosphorylation, organism-specific biosystem; Wnt signaling network, organism-specific biosystem;
MIM	300556

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