Human APEX2 Knockdown Cell Line - Glioma

Name: Human APEX2 Knockdown Cell Line - Glioma
SKU: CSC-RK0227
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RK0227

Host Cell : Glioma Validation : Real-Time RCR

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RK0227
Description	This cell line is engineered to stably express shRNA targeting human APEX2.
Target Gene	APEX2
Host Cell	Glioma
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Storage	Liquid nitrogen
Shipping	Dry ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 [ Homo sapiens ]
Gene Symbol	APEX2
Synonyms	APE2; XTH2; APEXL2
Gene Description	APEX nuclease (apurinic/apyrimidinic endonuclease) 2
Gene ID	27301
Uni Prot ID	E5KN95
m RNA Refseq	NM_014481.2
Protein Refseq	NP_055296.2
Chromosome Location	Xp11.21
Function	DNA binding; DNA-(apurinic or apyrimidinic site) lyase activity; endonuclease activity; exonuclease activity; zinc ion binding;
Pathway	BER complex, organism-specific biosystem; BER complex, conserved biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem;
MIM	300773

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