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UPK1A


Official Full Name
uroplakin 1A
Organism
Homo sapiens
Gene ID
11045
Background
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Synonyms
UP1A; UPIA; UPKA; TSPAN21

Cat.No. Product Name Price
SHH440777 shRNA set against Human UPK1A (NM_007000.2) Inquiry
SHH440784 shRNA set against Rat UPK1A (NM_001108911.1) Inquiry
SHL115550 shRNA set against Mouse Upk1a(NM_026815.2) Inquiry
SHW009615 shRNA set against Danio rerio UPK1A (NM_001040242) Inquiry
SHH440780 shRNA set against Mouse UPK1A (NM_026815.2) Inquiry
SHL115632 shRNA set against Human UPK1A(NM_007000.2) Inquiry
Cat.No. Product Name Price
CDCB157926 Human UPK1A ORF clone (BC107098) Inquiry
CDCB189658 Rabbit UPK1A ORF clone (XM_002722222.2) Inquiry
CDCR294167 Human UPK1A ORF Clone(NM_007000.2) Inquiry
CDFH020881 Human UPK1A cDNA Clone(NM_007000.2) Inquiry
CDFR008477 Rat Upk1a cDNA Clone(NM_001108911.1) Inquiry
MiUTR1H-11026 UPK1A miRNA 3'UTR clone Inquiry
MiUTR1M-12477 UPK1A miRNA 3'UTR clone Inquiry
CDCB171090 Danio rerio UPK1A ORF Clone (NM_001040242) Inquiry
CDCR259315 Mouse Upk1a ORF Clone(NM_026815.2) Inquiry
CDCR375512 Rat Upk1a ORF Clone(NM_001108911.1) Inquiry
CDCS413017 Human UPK1A ORF Clone (BC107098) Inquiry
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