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NR1H3


Official Full Name
nuclear receptor subfamily 1 group H member 3
Organism
Homo sapiens
Gene ID
10062
Background
The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Synonyms
LXRA; LXR-a; RLD-1

Cat.No. Product Name Price
SHR020040 shRNA set against Rat Nr1h3(NM_031627.2) Inquiry
SHW008214 shRNA set against Danio rerio NR1H3 (NM_001017545) Inquiry
SHH354672 shRNA set against Human NR1H3 (NM_005693.3) Inquiry
SHH354676 shRNA set against Mouse NR1H3 (NM_013839.4) Inquiry
SHH354680 shRNA set against Rat NR1H3 (NM_031627.2) Inquiry
SHR020047 shRNA set against Human NR1H3(NM_001130102.2) Inquiry
SHW005054 shRNA set against Chicken NR1H3 (NM_204542) Inquiry
Cat.No. Product Name Price
CDCR242707 Mouse Nr1h3 ORF Clone(NM_001177730.1) Inquiry
CDCR349465 Human NR1H3 ORF Clone(NM_001130101.2) Inquiry
CDCR379784 Rat Nr1h3 ORF Clone(NM_031627.2) Inquiry
CDFR012781 Rat Nr1h3 cDNA Clone(NM_031627.2) Inquiry
MiUTR1H-06893 NR1H3 miRNA 3'UTR clone Inquiry
MiUTR1R-04272 NR1H3 miRNA 3'UTR clone Inquiry
MiUTR3H-04967 NR1H3 miRNA 3'UTR clone Inquiry
MiUTR3H-04969 NR1H3 miRNA 3'UTR clone Inquiry
CDCB166529 Chicken NR1H3 ORF Clone (NM_204542) Inquiry
CDCB169689 Danio rerio NR1H3 ORF Clone (NM_001017545) Inquiry
CDCB180903 Rabbit NR1H3 ORF clone (XM_008268625.1) Inquiry
CDCL139651 Human NR1H3 ORF clone (NM_001251934.1) Inquiry
CDCR252466 Mouse Nr1h3 ORF Clone(NM_013839.4) Inquiry
CDCR349466 Human NR1H3 ORF Clone(NM_001130102.2) Inquiry
CDCS407914 Human NR1H3 ORF Clone (BC008819) Inquiry
CDCS407915 Human NR1H3 ORF Clone (BC041172) Inquiry
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