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CTNNB1


Official Full Name
catenin beta 1
Organism
Homo sapiens
Gene ID
1499
Background
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
Synonyms
EVR7; CTNNB; MRD19; NEDSDV; armadillo

Cat.No. Product Name Price
AD04362Z Human CTNNB1 adenoviral particles Inquiry
Cat.No. Product Name Price
SHH271313 shRNA set against Mouse CTNNB1 (NM_007614.3) Inquiry
SHG171685 shRNA set against Human CTNNB1(NM_001904.3) Inquiry
SHG171739 shRNA set against Rat Ctnnb1(NM_053357.2) Inquiry
SHH271309 shRNA set against Human CTNNB1 (NM_001904.3) Inquiry
SHH271317 shRNA set against Rat CTNNB1 (NM_053357.2) Inquiry
SHW005581 shRNA set against Chicken CTNNB1 (NM_205081) Inquiry
SHW014573 shRNA set against Danio rerio CTNNB1 (NM_131059) Inquiry
Cat.No. Product Name Price
SKO0099 CTNNB1 Validated sgRNA vector Inquiry
MiUTR1H-02527 CTNNB1 miRNA 3'UTR clone Inquiry
MiUTR1H-02526 CTNNB1 miRNA 3'UTR clone Inquiry
MiUTR1H-02525 CTNNB1 miRNA 3'UTR clone Inquiry
CDFR013112 Rat Ctnnb1 cDNA Clone(NM_053357.2) Inquiry
CDFH004454 Human CTNNB1 cDNA Clone(NM_001098209.1) Inquiry
CDCR243950 Mouse Ctnnb1 ORF Clone(NM_007614.3) Inquiry
CDCR346444 Human CTNNB1 ORF Clone(NM_001098210.1) Inquiry
MiUTR1R-01255 CTNNB1 miRNA 3'UTR clone Inquiry
CDFH004453 Human CTNNB1 cDNA Clone(NM_001098210.1) Inquiry
CDCR380199 Rat Ctnnb1 ORF Clone(NM_053357.2) Inquiry
CDCL183776 Human CTNNB1 ORF clone(NM_001098209.1) Inquiry
CDCB180572 Rabbit CTNNB1 ORF clone (XM_008260260.1) Inquiry
CDCB176048 Danio rerio CTNNB1 ORF Clone (NM_131059) Inquiry
CDCB167056 Chicken CTNNB1 ORF Clone (NM_205081) Inquiry
CDCR240869 Mouse Ctnnb1 ORF Clone(NM_001165902.1) Inquiry
CDCB157166 Mouse CTNNB1 ORF clone (NM_007614.2) Inquiry
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