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LILRB4


Official Full Name
leukocyte immunoglobulin like receptor B4
Organism
Homo sapiens
Gene ID
11006
Background
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
B4; ILT3; LIR5; CD85K; ILT-3; LIR-5

Cat.No. Product Name Price
SHH330315 shRNA set against Human LILRB4 (NM_006847.3) Inquiry
SHH330323 shRNA set against Rat LILRB4 (NM_001013894.1) Inquiry
SHH149717 shRNA set against Human LILRB4(NM_006847.3) Inquiry
SHH149735 shRNA set against Human LILRB4(NM_001081438.1) Inquiry
SHH149753 shRNA set against Mouse Lilrb4(NM_013532.2) Inquiry
SHH330319 shRNA set against Mouse LILRB4 (NM_013532.2) Inquiry
Cat.No. Product Name Price
CDCS412948 Human LILRB4 ORF Clone (BC026309) Inquiry
CDFH010390 Human LILRB4 cDNA Clone(NM_001081438.1) Inquiry
CDFR002973 Rat Lilrb4 cDNA Clone(NM_001013894.1) Inquiry
MiUTR1H-05678 LILRB4 miRNA 3'UTR clone Inquiry
MiUTR1H-05679 LILRB4 miRNA 3'UTR clone Inquiry
MiUTR1M-06646 LILRB4 miRNA 3'UTR clone Inquiry
MiUTR1R-02196 LILRB4 miRNA 3'UTR clone Inquiry
CDCL127251 Mouse LILRB4 ORF clone (NM_001081438.1) Inquiry
CDCL127253 Human LILRB4 ORF clone (NM_006847.3) Inquiry
CDCL127259 Mouse Lilrb4 ORF clone (NM_013532.2) Inquiry
CDCR370050 Rat Lilrb4 ORF Clone(NM_001013894.1) Inquiry
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