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Gene editing is a genetic engineering technique, which is pointed to a sequence without knowing the function of it, by altering the genetic gene of a living organism to reduce the effect of a particular gene function. By studying the effects on the organism, we can find the biological function of genes.
Solid Technology
Roche 454
Illumine
It has been over 30 years since the first generation of DNA sequencing technology was developed in 1977. During this period, sequencing technology has made considerable progress. From the first generation to the third generation and even the fourth generation, sequencing technology has experienced the read length from long to short, and short to long. Although the second generation---short-read sequencing technology still dominates the current global sequencing market, the third and fourth generation of sequencing technologies are rapidly evolving over the course of the two-year period. Every transformation of sequencing technology results in a huge role in promoting genome research, disease medical research, drug development, breeding and other fields. This blog is mainly focusing on the current genome sequencing technologies and their sequencing principles.
miRNA sponge functional model plays a very significant role in biological researches. In this blog, we mainly introduce professor Rajewsky Nikolaus, who have contributed a lot for the circular RNA function study.
