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PRNP


Official Full Name
prion protein (Kanno blood group)
Organism
Homo sapiens
Gene ID
5621
Background
The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Synonyms
CJD; GSS; PrP; ASCR; KURU; PRIP; PrPc; CD230; AltPrP; p27-30; PrP27-30; PrP33-35C

Cat.No. Product Name Price
SHH219678 shRNA set against Human PRNP(NM_000311.3) Inquiry
SHH219696 shRNA set against Human PRNP(NM_183079.2) Inquiry
SHH383416 shRNA set against Human PRNP (NM_183079.2) Inquiry
SHH383420 shRNA set against Mouse PRNP (NM_011170.2) Inquiry
SHH383424 shRNA set against Rat PRNP (NM_012631.2) Inquiry
SHR141594 shRNA set against Rat Prnp(NM_012631.2) Inquiry
SHW005957 shRNA set against Chicken PRNP (NM_205465) Inquiry
Cat.No. Product Name Price
CDCS405570 Human PRNP ORF Clone (BC022532) Inquiry
MiUTR3H-01828 PRNP miRNA 3'UTR clone Inquiry
MiUTR1R-06085 PRNP miRNA 3'UTR clone Inquiry
MiUTR1H-08301 PRNP miRNA 3'UTR clone Inquiry
MiUTR1H-08300 PRNP miRNA 3'UTR clone Inquiry
CDFR010449 Rat Prnp cDNA Clone(NM_012631.2) Inquiry
CDFH015188 Human PRNP cDNA Clone(NM_001080123.1) Inquiry
CDFH015187 Human PRNP cDNA Clone(NM_001080122.1) Inquiry
CDFH015186 Human PRNP cDNA Clone(NM_001080121.1) Inquiry
CDCS405571 Human PRNP ORF Clone (BC012844) Inquiry
MiUTR3H-01830 PRNP miRNA 3'UTR clone Inquiry
CDCR345519 Human PRNP ORF Clone(NM_001080122.1) Inquiry
CDCL185851 Mouse PRNP ORF clone(NM_011170.2) Inquiry
MiUTR3H-01829 PRNP miRNA 3'UTR clone Inquiry
CDCR345521 Human PRNP ORF Clone(NM_001080123.1) Inquiry
CDCR345517 Human PRNP ORF Clone(NM_001080121.1) Inquiry
CDCR279927 Human PRNP ORF Clone(NM_000311.3) Inquiry
CDCL185852 Rat PRNP ORF clone(NM_012631.2) Inquiry
CDCB180209 Rabbit PRNP ORF clone (XM_008256135.1) Inquiry
CDCB167432 Chicken PRNP ORF Clone (NM_205465) Inquiry
CDCB160272 Human PRNP ORF clone (NM_000311) Inquiry
CDCB156629 Cynomolgus PRNP ORF clone Inquiry
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