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VCL

Official Full Name
vinculin
Background
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Synonyms
VCL; vinculin; MV; MVCL; CMD1W; CMH15; HEL114; metavinculin; epididymis luminal protein 114

Cat.No. Product Name Price
CLOE-1792Human VCL HEK293 Cell LysateInquiry
CLOE-2458Mouse Vcl HEK293 Cell LysateInquiry

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