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UBA3


Official Full Name
ubiquitin like modifier activating enzyme 3
Organism
Homo sapiens
Gene ID
9039
Background
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
NAE2; UBE1C; hUBA3

Cat.No. Product Name Price
SHH438660 shRNA set against Human UBA3 (NM_003968.3) Inquiry
SHH438664 shRNA set against Mouse UBA3 (NM_011666.2) Inquiry
SHH438668 shRNA set against Rat UBA3 (NM_057205.2) Inquiry
SHW018521 shRNA set against Danio rerio UBA3 (NM_213467) Inquiry
Cat.No. Product Name Price
CDFG012645 Human UBA3 cDNA Clone(NM_198195.1) Inquiry
CDFG019104 Mouse Uba3 cDNA Clone(NM_001111106.1) Inquiry
CDFH020709 Human UBA3 cDNA Clone(NM_003968.3) Inquiry
CDFR013783 Rat Uba3 cDNA Clone(NM_057205.2) Inquiry
MiUTR1H-10927 UBA3 miRNA 3'UTR clone Inquiry
MiUTR1H-10928 UBA3 miRNA 3'UTR clone Inquiry
MiUTR1M-12372 UBA3 miRNA 3'UTR clone Inquiry
MiUTR1R-08306 UBA3 miRNA 3'UTR clone Inquiry
CDCB179996 Danio rerio UBA3 ORF Clone (NM_213467) Inquiry
CDCB191732 Rabbit UBA3 ORF clone (XM_002713306.2) Inquiry
CDCH097194 human UBA3 ORF clone (NM_198195.1) Inquiry
CDCH097196 human UBA3 ORF clone (NM_003968.3) Inquiry
CDCH097198 Mouse Uba3 ORF clone (NM_011666.2) Inquiry
CDCH097200 Mouse Uba3 ORF clone (NM_001111106.1) Inquiry
CDCR380816 Rat Uba3 ORF Clone(NM_057205.2) Inquiry
CDCS411564 Human UBA3 ORF Clone (BC022853) Inquiry
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